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Which of the following is a risk factor for developing breast cancer that can be evaluated by mammography?

  1. Family history of breast cancer

  2. High cholesterol levels

  3. Frequent headaches

  4. Irregular menstrual cycles

The correct answer is: Family history of breast cancer

A family history of breast cancer is a significant risk factor that can be evaluated through a person's medical and family history in conjunction with mammography. Mammography screening is primarily used to detect breast cancer at an early stage, and it is crucial for individuals with a family history, as they may be at a higher risk for developing the disease. While family history alone cannot be quantified solely by mammography, it influences the recommendations for the frequency and initiation of screening. These patients might be advised to begin screening at an earlier age or to have additional imaging studies to ensure thorough monitoring. This context highlights the importance of integrating personal and family medical history into breast cancer screening protocols, which is vital for effective risk management in individuals identified as high-risk. The other options, such as high cholesterol levels, frequent headaches, and irregular menstrual cycles, do not directly correlate with breast cancer risk in the same way. High cholesterol is related to cardiovascular health, while frequent headaches and irregular menstrual cycles pertain to different health concerns altogether. These factors might affect overall health but are not evaluated through mammography for breast cancer risk assessment.