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In a patient with heart disease, a prominent P wave may suggest which condition?

  1. Atrial enlargement

  2. Ventricular hypertrophy

  3. Myocardial infarction

  4. Heart block

The correct answer is: Atrial enlargement

A prominent P wave on an electrocardiogram (ECG) often indicates atrial enlargement. This can occur in conditions where there is increased pressure or volume load on the atria, such as in heart disease. The P wave represents atrial depolarization, and when the atria are enlarged, it takes longer for the electrical impulses to travel through them, leading to a larger and possibly peaked P wave. In patients with atrial enlargement, it's common to see conditions like mitral stenosis or chronic lung disease which can lead to right atrial enlargement, or conditions causing left atrial enlargement such as mitral regurgitation. Understanding this relationship helps in diagnosing underlying conditions in patients with heart disease and can lead to better-targeted treatments.